Mrs. K.Naveena

AREAS OF INTEREST

• Insilico drug designing, Molecular Modeling, Simulations.

• Understanding the behavior of Biological systems and drugs through Kinetic modeling.

• Targeting structural proteins in cancer through computer aided drug Designing

Publications

• “Synthesis, Antimicrobial and Antioxidant Evaluation of Some Bis (Indolyl) Methane Derivatives” T. Sathish Kumar, D. Sathis Kumar, Venkata Krishna, K. Naveena, M. Raginiand A.Harani “Asian Journal of Chemistry”.
• Molecular docking studies of withanolides against Cox-2 enzyme. Pakisthan Journal of pharmaceutical sciences. Yogeswaran P, K.Naveena
• Won Best Poster presentation at saveetha Dental College for Mutational analysis of Brugia malayi AsnRs
• Curated 2 kinetic reaction model Molecular habituation’ as a potential mechanism of gradual homeostatic loss with age MODEL 2 & MODEL 4 in Biomodel database using COPASI.
• Selected and delivered Oral Presentation on Identification of Novel Lysyl Hydroxylase Inhibitors & their Molecular Insights – a computational Approach at 5th IIT Madras –Tokyo Tech Joint Symposium on “Current trends in Bioinformatics: Big data analysis, Machine Learning and drug design”

DRUG DESIGN SOFTWARE’S & TOOLS

• Simulation software: GROMACS, Schrodinger- Desmond
• Kinetic Simulator: COPASI, CELL DESIGNER
• Docking and QSAR software’s:, Schrodinger- Glide, TRIPOS Sybyl , Hex, AUTODOCK
• Protein- Protein Docking – CLUSPRO
• Homology modeling Tool: Modeler, Schrodinger –prime, I-Tasser, Quark
• Abinitio Modeling Tool- Robetta
• Biochemical Network Interaction Software: Cytoscape, String Database
• Pharmacophore modelling: Ligand scout
• Molecular Visualization Software: Rasmol, Chimera, PYMOL, SwissPdb viewer
• Database & Tools: EMBL - Biomodel, BLAST, Clustal package, Phylogenetic analysis, SNP analysis, CASTP server, QSITE binder.
• Cheminformatics Tools & Databases: Schrodinger Phase, ZINC, Chem office 10.0, Chem Draw, Molinspiration, Molsoft, Argus lab.
• BIOLOGICAL DATABASES: NCBI, GENBANK, Swissprot, PDB

TRAINING PROJECTS & SYMPOSIUM ATTENDED

• Attended 1 week training in Kinetic Modeling & Biomodel Database at IIT Madras.
• Attended 1week training program in NEXT GEN SEQUENCING at Bio Discovery Group Life sciences (BDG).
• Attended 4 Global Initiative of Academic Networks (GIAN) programme at Anna University.
• Attended 2 Biotechnology Information Technology Systems (BTIS) at Anna University.
• 1year M.Pharm project in computer aided drug designing at NIPER Ahmedabad, Gujarat.
• Undergone Industrial Training in PHARM PRODUCTS THANJAVUR.
• One month Industrial Training in MEIR’S PHARMA, KARAIKAL
• Undergone short term HANDS ON Training in Isolation of DNA, PCR Technique,
• GEL Electrophoresis, DNA Fingerprinting at SIMPRA Biotechnology institute, Thanjavur.

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